Pingault Lab

University College London

- · United Kingdom

ERC-funded
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ERC Consolidator Grant · 2019

From parental risk to child mental illness: a genetically informed investigation of intergenerational risk pathways

Mental illnesses account for 32% of years lived with disability. Critically, 50% of mental illnesses are established before age 14 years. It is thus imperative to better understand the causes of early psychiatric symptoms in childhood if we are to design effective preventive interventions. Parental risk factors –e.g. psychiatric disorders and substance use– have consistently emerged as strong predictors of child psychiatric symptoms. However, we do not know whether such parental risk factors are causes or mere correlates of child symptoms and how this transmission of risk across generations occurs. The overarching aim of I-RISK is to identify causal intergenerational pathways linking…

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