Pellissier Lab

Research focus

ERC Starting Grant · 2019

New molecular targets and proof-of-concept therapies for Autism Spectrum Disorders

Autism is the major neurodevelopmental health public issue, affecting 1/100 child births worldwide. These disorders are diagnosed before the age of 3, based on behavioural cues: deficits in social interaction and communication as well as stereotyped and restrained behaviours. There is no medication to improve this condition. Most recent molecular targets identified within narrow frameworks (unspecific molecule, single tissue targeted, single disease model used) have failed in clinical trials. My first objective aims at thwarting this autism research gap, unravelling the common molecular and cellular dysfunctions underlying autism-related behaviours across several preclinical models and…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.