Grieve Lab

Foundation of Scientific Cooperation for Hearing and Seeing

Ile-de-France (FR1) · France

ERC-funded
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Research focus

ERC Consolidator Grant · 2020

Optical imaging of retinal function for gene and cell therapies

For patients suffering from inherited retinal diseases (IRDs), gene and cell therapies offer hope of preserving or restoring vision. Retinal imaging is crucial, to first phenotype patients to determine which cells are degenerated and devise an appropriate therapeutic path; then in the lab for cell therapy development, and finally back in the clinic to monitor therapeutic success in patients who have been treated with gene or cell therapy. To date, the imaging tools used in the clinic do not provide sufficient resolution for visualizing individual cells non-invasively, constituting a major roadblock for the development of gene and cell therapies. My group develops novel optical imaging tools…

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