ERC Consolidator Grant · 2020
Facing Adiposity in personalizing Treatment of Breast Cancer Patients
One out of 8 women develops breast cancer (BC) in her lifetime and 1 out of 2 is overweight or obese in industrialized countries. While heavier women have an increased risk of developing BC and heavier BC patients present with worse disease characteristics, BC is so far still treated regardless of patient adiposity because of the limited knowledge accumulated so far. I hypothesize that increased adiposity provides a different ‘soil’ for the tumor cells (the 'seeds') to grow, potentially leading to biological peculiarities of the tumor cells and the cells from the tumor microenvironment. To investigate this hypothesis, I will firstly study the associations between patient adiposity and the…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.