Chesnais Lab

Development Research Institute (IRD)

Provence-Alpes-Côte d’Azur (FRL) · France

ERC-funded
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ERC Starting Grant · 2020

Morbidity due to Loiasis: population-wide evaluation and identification of pathogenic mechanisms

Loiasis, an infectious disease caused by the parasitic worm Loa loa, affects more than 15 million individuals in central Africa, and more than 100 million people are potentially exposed to infection. Since its first description in 1770, the international scientific community has considered this filarial disease as benign. I recently demonstrated that loiasis significantly reduces the life expectancy of infected people. I aim to definitively shift the prevailing paradigm of “benign loiasis” by showing that it can induce severe complications in various organs. I will conduct the first population-wide evaluation of morbidity in rural areas of Central Africa by performing systematic…

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