ERC Starting Grant · 2020
Disrupted Circadian Rhythms in Families - an Endophenotype of Autism Spectrum Disorder?
Sleep disturbances are highly prevalent in children with neurodevelopmental disorders, and this adversely impacts the whole family’s wellbeing. While the origins of neurodevelopmental disorders are considered largely genetic, the mechanisms that underlie sleep disruption, and their relationship to neurodevelopment, is relatively unexplored. Chronotype is our daily preference for morning or evening time, and a recent large-scale genome-wide association study highlighted its significant relationship with the most common neurodevelopmental disorder, autism spectrum disorder (ASD). Chronotype is an indication of our circadian rhythms, which alongside environmental factors, influences sleep…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.