ERC Starting Grant · 2020
Depression in diverse populations: Unravelling the interplay between genes and environment
Depression affects 300 million people and represents one of the biggest challenges to human health to date. Of the burden, 80% pertains to low- and middle-income countries. It is thus imperative to understand the global causes of depression to design effective targeted interventions. DIVERGE will build the first ancestrally diverse data resource for depression, generated from biobanks (N=1.8M) and new studies in Pakistan (N=20K) as well as sub-Saharan Africa (N=13K) with deep phenotyping and genotyping. Differences in depression risk between populations have been shaped by the environment, demography and diverging evolutionary history. Using the novel perspective of evolutionary psychiatry,…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.