ERC Advanced Grant · 2021
Modelling trajectories and mechanisms of childhood hip dysplasia
With 40 million patients in Europe, osteoarthritis (OA) is the most common chronic and disabling disease. OA is incurable, and symptomatic treatments have limited effect. Therefore, prevention by identifying and targeting asymptomatic persons that develop a clear OA risk factor is sorely needed. Hip dysplasia is the strongest risk factor for hip OA. Hip dysplasia is a condition of mechanical instability of the hip caused by insufficient coverage of the femoral head (ball) by a shallow or obliquely oriented acetabulum (socket). This results in high cartilage stress, and subsequent hip OA. In Europe we screen for developmental hip dysplasia in infants (prevalence 2%), enabling early…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.