Pijnappels Lab

Leiden University Medical Center

West-Nederland (NL3) · Netherlands

ERC-funded
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ERC Consolidator Grant · 2021

Translational optoelectronic control of cardiac rhythm in atrial fibrillation

It’s my conviction that, one day, we will enable the human heart to terminate its own rhythm disturbances and thereby restore its normal rhythm at any place and time. Such acute restoration of cardiac rhythm would not be based on traumatizing electric shocks, but on generation of bioelectricity by the affected heart itself. In order to explore this paradigm-changing approach for ambulatory shock-free control of cardiac rhythm, I will integrate the unique advances of genetic engineering, computer modelling, tissue engineering and micro-optoelectronics. To determine the advanced and translational potential of such optoelectronic heart rhythm control, the most prevalent cardiac arrhythmia will…

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