Dyrby Lab

Research focus

ERC Consolidator Grant · 2021

Non-invasive Conduction Velocity Mapping in Brain Networks: A novel imaging framework for axonal fingerprinting of brain connections in health and disease

Axonal bundles in cerebral white matter form the structural basis of functional brain networks, enabling effective integration of neural activity. The axonal connections are not homogenous structures. Axons differ in diameter and myelination, enabling signal conduction at different velocities. This axonal diversity is a clinically relevant microstructural feature, as neurodegenerative or neuroinflammatory processes can affect axon diameters differently. Recent advances in Magnetic Resonance Imaging (MRI) have enabled the non-invasive mapping of the microstructural properties of brain network connections in live brains. But attempts to correlate these structural features with brain function…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.