Marcatili Lab

National Centre for Scientific Research (CNRS)

Ile-de-France (FR1) · France

ERC-funded
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ERC Starting Grant · 2021

Prompt Gamma Time Imaging: a new medical-imaging modality for adaptive Particle Therapy

Particle Therapy (PT) is potentially the most conformal and selective form of radiotherapy, but its clinical outcome is still limited, mainly because of the numerous sources of uncertainties affecting both treatment planning and delivery. The objective technical complexity of predicting and verifying the ion path in the patient has led to conservative treatments that, in order to increase safety, sacrifice efficacy. Having the full control of the dose gradient within the patient in real time would allow to fully exploit the ballistic advantage of PT. The healthy-tissue sparing effect can be enormous, further encouraging the use of PT for paediatric malignancies. Alternatively, the target…

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