Papadacci Lab

National Institute of Health and Medical Research (INSERM)

Ile-de-France (FR1) · France

ERC-funded
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ERC Starting Grant · 2021

Whole-organ 3D ultrasound micro-flow imaging: from basics physics to clinical proof-of-concept on cardiac and cerebral diseases

Blood circulation is essential to organs’ functions and occurs through a complex network of vessels with diameters varying from several millimetres for large arteries to only a few microns for small capillaries. Dysfunctions in the microcirculation are early markers of many diseases, which are however diagnosed at later stage, when observable symptoms become visible at larger scales. Mapping blood flows across several spatial scales at depth in organs is therefore crucial for early diagnosis and monitoring of diseases, but it remains a major challenge in clinical medical imaging. Our laboratory Physics for Medicine Paris has introduced in 2015 ultrasound localization microscopy (ULM), a…

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