Bogner Lab

University of Medicine Vienna

Ostösterreich (AT1) · Austria

ERC-funded
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Research focus

ERC Consolidator Grant · 2022

Deuterium labeling of GLUCOse improves magnetic resonance imaging Sensitivity to CANcer metabolism

The targeted scientific breakthrough of GLUCO-SCAN is the development and clinical evaluation of a disruptive whole-body molecular imaging concept for cancer assessment. The only currently established whole-body molecular imaging device is positron emission tomography (PET). Glucose (Glc)-sensitive PET is widely used in cancer diagnosis and treatment assessment, but has several major limitations: PET involves harmful ionizing radiation, is expensive, not widely available, and cannot differentiate between cancer-specific and normal cellular glucose uptake. These limitations prohibit an even more widespread use of PET, e.g. for screening. We propose a new Magnetic Resonance Imaging (MRI)…

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