Sauvage Lab

Ghent University

Vlaams Gewest (BE2) · Belgium

ERC-funded
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ERC Starting Grant · 2022

Pulsed Laser Light and Nano-encapsulated Ocular Dyes for Advanced Therapies in the Eye

Ocular diseases affect the quality of life of millions of patients. Despite improvements in pharmacological treatments, the arsenal of medications to treat severe ocular diseases today remains rather restricted to traditional drugs. Use of most modern biotherapeutics like proteins and nucleic acids, could be a major step forward. However, current ways of administration such as eye drops and intravitreal injections, are no longer sufficient to deliver these drugs to most targets in the eye. Therefore, novel concepts allowing biotherapeutics to safely overcome ocular barriers are of high interest. In ocular surgery, pulsed-lasers (P-Ls) are used for ‘tissue cutting’, though safety concerns…

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