Jochems Lab

Leiden University Medical Center

West-Nederland (NL3) · Netherlands

ERC-funded
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Research focus

ERC Starting Grant · 2022

Understanding respiratory tract infections through minimally-invasive, daily nasal sampling in children

Pneumonia is the number one infectious cause of death in children worldwide. Many of the viruses and bacteria that cause pneumonia regularly infect, or colonize, the upper respiratory tract (URT) without causing disease. This drives community transmission but is also an important source of immunity. The processes and key host immune and microbiota factors that determine the infection kinetics, transmission and development of immunity during such infections need elucidation. I have recently optimized minimally-invasive nasal sampling analysis methods using Synthetic Absorptive Matrix (SAM) strips that now allow me to address these knowledge gaps. Through the daily collection of such…

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