ERC Starting Grant · 2023
Transformative Pediatric Brain Cancer Imaging using Integrated Biophysics-AI Molecular MRI
Despite vast drug development efforts, brain tumors remain the leading cause of pediatric cancer deaths. Noninvasive monitoring of treatment response is crucial to reveal the mechanisms behind tumor-drug interactions and optimize patient care. However, standard magnetic resonance imaging (MRI) methods involve injecting metals, have severe difficulties in differentiating treatment response from tumor progression, are qualitative, and mandate prolonged anesthesia due to the lengthy acquisition. I propose to develop a transformative molecular MRI technology, based on the chemical exchange saturation transfer (CEST) contrast mechanism that will enable specific, quantitative, rapid,…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.