Langkammer Lab

Medical University of Graz

Südösterreich (AT2) · Austria

ERC-funded
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Research focus

ERC Consolidator Grant · 2024

Elemental and Structural Composition underlying Brain MRI

Magnetic Resonance Imaging (MRI) is widely established, with 50,000 scanners worldwide and more than 100 million diagnostic scans conducted yearly. Myelin acts as the electrical insulation of neuronal fibers and is essential for motor, sensory, and cognitive functions and is composed of several lipids and proteins arranged in a specific geometry. However, myelin loss occurs regionally in inflammatory diseases like multiple sclerosis, myelitis, and optic neuritis, and it also serves as a biomarker of aging. Despite the availability of various MRI-based approaches for detecting myelin, there remains a significant gap in systematically validated knowledge regarding how myelin's lipids,…

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