Lu Lab

Karolinska Institute

Östra Sverige (SE1) · Sweden

ERC-funded
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ERC Starting Grant · 2024

Unveiling the Molecular Secrets of Reproductive Mood Disorders: a Multi-Omics Approach Project

Reproductive mood disorders (RMDs), including premenstrual disorder and postpartum depression, have a significant impact on women and their families, contributing to the well-known gender gap in mental health. However, effectively diagnosing and treating RMDs remains an ongoing challenge. These conditions are closely tied to hormonal changes during menstruation and childbirth, indicating a shared vulnerability. While the precise mechanisms are not yet fully understood, emerging data, including my work, supports the hypothesis that genetic predisposition, chronic inflammation, and metabolic dysfunction play pivotal roles in the development of RMDs. The MoodMAP project aims to discover novel…

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