ERC Starting Grant · 2025
Informed ecological rewiring of gut microbiome for dysbiosis-associated disorders
Gut microbiome disruption contributes to the so-called “dysbiosis-associated disorders”. Although the interindividual variability and plasticity of microbiome support its precise modulation, to date only untargeted treatments are available, mostly with inconsistent results. My preliminary data hint that tailored microbial therapy, guided by microbiome profiling, may improve post-infectious irritable bowel syndrome (PI-IBS), a common but understudied dysbiosis-associated disease. MicroRestore aims to prove that metagenome-informed ecological rewiring of gut microbiome can improve dysbiosis-associated disorders, using PI-IBS as disease model. I will apply a comprehensive multimodal approach,…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.