ERC Starting Grant · 2017
Microsatellite Barcoding: reconstructing the family tree of hematopoietic cells
While murine hematopoiesis has been considered as resolved science, recent results using barcoding, that allows the tracing of single cells in vivo, clearly show that the topology of the murine hematopoietic tree needs revisions. In parallel, human hematopoiesis has been overlooked and is widely considered as following the same tree as mice. To leverage our understanding of normal human hematopoiesis tools for barcoding in human are urgently needed. This research program seeks to overcome this methodological barrier by taking advantage of recent developments in next generation sequencing and develop a barcoding method, called microsatellite barcoding, to be used in vivo in human. Our method…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.