ERC Starting Grant · 2017
The Mechanisms and Dynamics Controlling Cycles of Lymph Node Expansion
Lymph node swelling is a classical hallmark of immunity. This expansion is observed by doctors, researchers and patients, yet as obvious as this process is, our understanding of the remodelling mechanisms involved are in their infancy. Lymph node remodelling is rapid and yet completely reversible, occurring countless times throughout our lifetimes. The purpose of this proposal is to understand how lymph node remodelling occurs and is resolved, repeatedly; to understand immunity in a whole organ context. The architecture of lymphoid organs is key to the effective operation of our immune system and is dictated by structures formed by non-haematopoetic stromal cells, including endothelial…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.