Huber Lab

University Medical Center Hamburg-Eppendorf

Hamburg (DE6) · Germany

ERC-funded
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Research focus

ERC Advanced Grant · 2023

Decode and Cure primary Focal Segmental Glomerulosclerosis

Kidney diseases are a worldwide rising major health problem associated with an excess risk for cardiovascular disease and reduced life expectancy. While general risk factors for kidney diseases such as diabetes and hypertension are being addressed through numerous research efforts, causes of specific glomerular kidney diseases, especially Focal Segmental Glomerulosclerosis (FSGS), remain poorly understood. FSGS is the most common glomerular cause of end stage renal disease characterized by scaring of the glomerular kidney filters and podocytes loss. Until now, the development of specific therapies has been hindered by the poor stratification of FSGS entities and the lack of understanding of…

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