ERC Advanced Grant · 2021
Illuminating the enteroviral life cycle
Enteroviruses are highly prevalent pathogens that have enormous clinical and socio-economic impact. Well-known examples are poliovirus, coxsackievirus, enterovirus-A71, enterovirus-D68, and rhinovirus. Although important insights have been obtained in the enteroviral life cycle, many important questions remain unanswered due to shortcomings of current imaging and biochemical methodologies. There is a high need for novel technologies that allow sensitive and real-time observation of the dynamics and localisation of viral RNA, viral proteins, and host factors at the single-cell level. My long-term goal is to understand enterovirus replication and translate knowledge into the development of…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.