ERC Consolidator Grant · 2021
Deciphering cellular and viral determinants of lytic HSV-1 infection, latency and reactivation
Herpes simplex virus 1 (HSV-1) is an important human pathogen which infects the majority of the world`s population and inflicts a substantial burden of disease. Over the past 10 years, systems biology approaches, to which my lab has provided seminal contributions, have substantially broadened our understanding of the complex interaction of this common pathogen with its human host. However, the underlying molecular mechanisms remain poorly understood and their importance for virus latency and reactivation remain elusive. Furthermore, currently available technology lacks the temporospatial resolution to decipher the cellular and viral determinants that govern the virus life cycle. The main…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.