Zielinski Lab

Research focus

ERC Consolidator Grant · 2024

Dissecting the body-wide spatio-temporal organisation of human resident T helper cells

T helper cells represent a heterogeneous population of immune cells that are critical for host defense and, if dysregulated, for pathologies such as autoimmunity and allergy. T cell responses take place in peripheral tissues. Yet, insights into their identity and regulation stem almost exclusively from investigations of circulating blood, which comprises only 2% of the total human T cell population. Accordingly, current immunomodulatory drugs act systemically, but lack tissue specificity. Despite progress in the temporary suppression of chronic inflammatory diseases, they still fail to be curative. This project aims to address this unmet medical need by generating fundamental insights into…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.