ERC Starting Grant · 2024
Infectious diseases caused >2 million deaths in 2019 (pre-COVID-19). Cancer patients die more often from infections than healthy individuals and are less effectively protected by vaccines. Several studies link oncology drugs to altered vaccine responses. While designed to inhibit tumor progression, these drugs also affect immune functions and thus may interfere with vaccine responses – for better or worse. A systematic analysis of this problem has so far been hampered by a lack of suitable models and the low throughput of clinical trials. Currently, it is unknown how most oncology drugs, routinely administered to patients, affect vaccine responses. In OrAIOn, I will fill this knowledge gap…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.