ERC Starting Grant · 2025
Origin and Development of the B cell response during Immunoregulatory Helminth Infections
One-fourth of the global population is currently infected with helminths, which modulate host immunity against not only their own antigens but also non-cognate antigens, including vaccines. While antigen-specific antibodies and memory B cells are essential for protection against infectious diseases, how the B cell response quality is influenced by helminths remains largely unknown. With my core expertise in studying responses to parasites at the level of single B cells and monoclonal antibodies, I aim to delineate the onset and quality of B cell responses formed during immunoregulatory helminth infections, impacting the development of effective vaccines. The B cell response quality relies…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.