ERC Starting Grant · 2017
Cooperative and competitive parallel memory units for choice behaviors
This proposal seeks to understand the molecular and circuit mechanisms used to store information in parallel memory units, and how these memories are integrated to guide action selection. We will use the Drosophila mushroom body (MB), a key center for associative learning in insect brains, as a model system. We recently generated intersectional genetic drivers that allowed us to draw a comprehensive anatomical map and selectively manipulate nearly all of the MB’s ~60 cell types. Sparse activity in the 2,000 Kenyon cells of the MB represents the identity of sensory stimuli. Along the parallel axonal fibers of Kenyon cells, we have shown that dopaminergic neurons and MB output neurons form 16…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.