Yanik Lab

Research focus

ERC Consolidator Grant · 2018

Engineering brain activity patterns for therapeutics of neuropsychiatric and neurological disorders

Neuropsychiatric and neurological disorders are complex dysfunctions of neuronal circuits. Their treatment has been limited by the lack of non-invasive methods for measuring the underlying circuit dysfunctions, and for direct and localized modifications of these circuits. We propose minimally invasive technologies for measuring brain activity and functional connectivity patterns, and for manipulating them directly in vivo to correct the abnormal behavioural phenotypes (in rodents with potential scalability to non-human primates and humans). First, we present a proof-of-principle study on mutant zebrafish, in which we correct whole-brain level abnormal activity patterns and behaviours by…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.