ERC Advanced Grant · 2019
Intrinsic and extrinsic determinants of neuronal identity
Neuronal diversity determines the variety of circuits that can be formed and thus sets the framework for an animal’s behavioural repertoire. During development, distinct neuronal types emerge from interactions between cell-intrinsic processes and cell-extrinsic processes. In the brain, untangling how intrinsic and extrinsic processes contribute to neuronal identity has been difficult, as neurons are highly interconnected and heterogeneous cells with distinct and dynamic sensitivities to environmental signals. In such conditions, high temporal single-cell resolution approaches are required to parse out the drivers of cell-type differentiation. The mouse neocortex is an ideal model to tease…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.