Hallermann Lab

University of Leipzig

Sachsen (DED) · Germany

ERC-funded
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Research focus

ERC Consolidator Grant · 2019

Molecular mechanisms of presynaptic plasticity

The ambitious goal of this project is to reveal the molecular mechanisms of presynaptic plasticity in the vertebrate brain. Synaptic plasticity occurs in the form of alterations in both presynaptic neurotransmitter release and postsynaptic receptor function. However, due to technical reasons and in contrast to intensely studied postsynaptic plasticity, the presynaptic half of the brain’s synaptic plasticity remains enigmatic. This is a crucial knowledge gap for our understanding of learning and memory. My ambitious aim is therefore to uncover the molecular and biophysical mechanisms of presynaptic plasticity. Building on my strong track record in presynaptic research, my group made a…

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