ERC Starting Grant · 2020
Alzheimer’s disease (AD) is the most common age-related neurodegenerative disease. Despite the significant progress made towards unpacking the pathomechanisms of AD, the molecular and cellular mechanisms underlying AD pathogenesis remain poorly understood. Previous studies mainly relied on animal models that do not capture human-specific biology, monolayer neural cultures that do not capture pathological hallmarks of the disease, and post-mortem tissues that only capture disease end-stage. There is thus a pressing need for new complementary approaches that preserve the disease genetics, mimic disease pathology, and more closely reflect human brain environment. I have developed a chimeric…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.