Shein-Idelson Lab

Tel Aviv University

- · Israel

ERC-funded
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Research focus

ERC Starting Grant · 2020

The Evolution and Function of Ancestral Brain States

One of the oldest enigmas in neuroscience is the function of brain states. During these states, dramatic transitions occur in the firing patterns of neurons in the cerebral cortex. These transitions are correlated with behaviour during wakefulness but, strikingly, are even more prominent during sleep, when interaction with the environment is limited. The similarities between sleep and awake patterns remains unexplained, thus complicating our understanding of the global function of brain states. Additionally, state transitions are prominent in both the cortex and hippocampus, but the interplay between these areas during different states remains ambiguous. Why is the function of brain states…

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