Felsenberg Lab

Research focus

ERC Starting Grant · 2020

Neural circuit mechanisms of memory destabilization

Memories can be rendered rewritable through a phenomenon called reconsolidation. The all-limiting step in this memory re-evaluation process is its initiation; the retrieval-dependent destabilization of the memory. However, the understanding of how a stable memory can be switched into a vulnerable but modifiable state is mostly in its infancy. Therefore, I aim to investigate the neural circuit mechanisms underlying retrieval-induced memory destabilization in the tractable fruit fly brain. A prerequisite to investigate the neural mechanisms involved in destabilizing a memory is to know where the learned information is stored and to have access to the associated network. Olfactory memories in…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.