Adam Lab

Hebrew University of Jerusalem

- · Israel

ERC-funded
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Research focus

ERC Starting Grant · 2020

All-Optical Dissection of Hippocampal Circuits Using Voltage Imaging

The hippocampus is critical for the storage of episodic memories and has been extensively studied on its role in spatial memory. The hippocampus is also a central model for in vitro studies on the molecular, cellular and microcircuit basis for learning and memory. I propose to use a new technology that I developed to record and manipulate the membrane potential of multiple neurons, simultaneously, in behaving animals to reveal the mechanisms by which hippocampal circuits process spatial information. This research will bridge the gap between the in vitro mechanistic studies and the in vivo efforts to describe the spatial representations. I first propose to employ the voltage imaging…

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