Cecil Lab

Erasmus Medical Center Rotterdam

West-Nederland (NL3) · Netherlands

ERC-funded
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ERC Starting Grant · 2021

Solving the 'time puzzle' of epigenetic effects on child mental health

TEMPO aims to solve the newly discovered epigenetic 'time puzzle' of child mental health. Recently it has been observed that common mental health problems in children (e.g. hyperactivity, poor impulse-control) are associated with epigenetic patterns at birth - a mechanism that regulates gene activity in response to genetic and environmental influences. Curiously, however, this association is lost when measuring the same epigenetic patterns later in development. This discovery is highly unexpected and potentially ground-breaking: the existence of timing effects could lead to new insights into the origins of mental health and open much-needed opportunities for early risk detection. Yet, what…

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