ERC Starting Grant · 2021
Epigenetic and transcriptional basis of memory engram plasticity
Neuroplasticity underlies learning and memory formation, which allows for accumulation of knowledge. There is an emerging view that a sparse ensemble of neurons, termed as engram cells, represent memory substrate and explain how memory is formed and retrieved. Extensive studies have been carried out to reveal molecular mechanisms regulating structural and synaptic plasticity of memory engram cells. However, there are still fundamental questions remaining to be solved regarding epigenetic and transcriptional basis of recent and remote memory formation, and heterogeneous identity specification of engram cells. To address these issues, I will carry out state-of-the-art genomics/epigenomics…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.