Ecker Lab

University of Goettingen

Niedersachsen (DE9) · Germany

ERC-funded
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ERC Starting Grant · 2021

Deep Neuron Embeddings: Data-driven multi-modal discovery of cell types in the neocortex

Understanding the relationship between structure and function of cortical neurons and circuits is one of the key challenges in neuroscience. For inhibitory neurons, roughly 15 subtypes are well characterized and we know a fair bit about their function. However, the vast majority of neocortical neurons are excitatory. Yet we know little about how differences in the morphology of excitatory neurons relate to their computational properties in vivo. I hypothesize that there is a close correspondence between morphology and function of excitatory neurons: distinct subtypes can be identified not only by their morphological features, but also by how they respond to stimulation with natural stimuli.…

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