Gross Lab

European Molecular Biology Laboratory (EMBL)

Baden-Württemberg (DE1) · Germany

ERC-funded
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ERC Advanced Grant · 2022

The neural basis of dynamic territorial aggression and fear

The urge to defend one’s territory is an evolutionarily conserved instinct aimed at securing optimal access to food, mates, and shelter. Conflict arises when territories become unstable due to seasonal changes in resource availability, or when population density increases. Under such conditions, individuals must carefully balance social aggression and avoidance to maximize their control of territorial resources while avoiding subordination at the hands of their neighbors. What is the neural basis of such dynamic territorial behaviors? We have found that an evolutionarily conserved medial hypothalamic brain structure serves as a switch between social aggression and avoidance. In this…

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