ERC Consolidator Grant · 2022
Resolving sEx DIffeREnces in proCessing sensory informaTion
Mental disorders are associated with abnormal sensory information processing (SIP) at preadolescence, especially in males. Aberrant SIP is a neutral cross-disorder trait that can be translated between humans and animals and assessed as the inability to prevent/gate an overload of irrelevant information. The mechanisms underlying physiological and pathological SIP variability are unexplored. Particularly, the causative role of hyperdopaminergia, key to SIP deficits, has never been tested by isolating, spatially and temporally, this single neural component. How does this trait evolve into a mental disorder? Why does it occur more often in males? REDIRECT will capitalize on our rodent model of…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.