ERC Consolidator Grant · 2022
The fascia is the largest tissue in the body, yet most of us never heard of it. This connective tissue delineates the skin, surrounds muscles, and closely envelops all organs. Clinically, it is mainly considered a mechanical barrier separating organs and muscles. But why should a simple barrier be populated with immune cells and receive extensive innervation by sensory and sympathetic neurons? Here we propose that the fascia generates a sensory platform that detects damage to the tissues it envelops and communicates this information to the brain which in turn, initiates corrective programs and modulates immune activity. Our preliminary results support this hypothesis indicating that chronic…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.