Jösch Lab

Institute of Science and Technology Austria

Ostösterreich (AT1) · Austria

ERC-funded
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ERC Consolidator Grant · 2022

Action Selection in the Midbrain: Neuromodulation of Visuomotor Senses

In an ever-changing natural world, animals must constantly adapt their behavior by extracting relevant information from the environment in a context-dependent manner. This is a complex task because the relevance of sensory stimuli rapidly changes according to the animal’s internal states, evidence, attention and goals. In the brain, neuromodulatory systems are thought to encode environmental and internal signals, such as novelty, reward, effort and risk, providing critical input to ensure appropriate action selection. However, classically, neuroscientists have opted to study sensorimotor transformations as a reflex arc, largely ignoring complex modulatory contributions due to their…

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