Poulet Lab

Max Delbrueck Center for Molecular Medicine

Berlin (DE3) · Germany

ERC-funded
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ERC Advanced Grant · 2023

Neuronal circuits for sensory-body state integration

Thermal homeostasis is essential to survival. But how our brain processes thermosensory information and triggers behaviors that help maintain our physiological, body state remains a mystery. The neural circuits responsible for perception of sensory stimulation and those for regulation of body state have been studied independently, yet body state has a profound impact on sensory perception. What is more, animals constantly adapt their behavior to maintain homeostasis with moment-by-moment sensing of the environment. Current models suggest that the insular cortex plays a key role in integrating internal information about body state with external sensory information about the environment to…

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