ERC Consolidator Grant · 2023
Vascular Interactions and Remodeling during Gestation and its Impact on Neuronal functions
An intricate network of blood vessels perfuses the brain to support neural cells and carry signaling molecules from the periphery. It is mainly considered a rigid “transportation network” rather than a dynamic and plastic “information network” integrated to neurons and glia. This proposal revisits this concept and aims to define the nature of vascular remodeling in healthy brains (i) and which remodeling mechanisms play a role in shaping plastic neuronal functions (ii) The project VIRGINS explores this in the context of the neurophysiological adaptations occurring during and after pregnancy. There, sexual hormones promote neuronal plasticity, which tunes the cerebral control of energy…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.
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