Zlatic Lab

University of Cambridge

- · United Kingdom

ERC-funded
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Research focus

ERC Advanced Grant · 2024

Discovering the circuit and molecular basis of inter-strain and inter-species differences in learning

Across the animal kingdom, closely-related species can differ in their learning ability, as can different individuals of the same species, but the underlying causes of these differences are poorly understood. Differences in learning could be due to different structural and functional properties of learning circuits which in turn result from different patterns of gene expression. However, identifying homologous learning circuit neurons in different species for comparing their synaptic connectivity, cellular-resolution functional properties and transcriptomes is challenging in larger brains. We have identified a strain of Drosophila melanogaster larvae that learns faster (after fewer training…

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