Ulanovsky Lab

Weizmann Institute

- · Israel

ERC-funded
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ERC Advanced Grant · 2024

Neuroscience in the real world: Representation of position, direction and environmental borders in the hippocampal formation of bats navigating outdoors on a remote oceanic island

Navigation is a key behavior, studied by multiple research fields. In ethology, wild animals are tracked outdoors using GPS tags as they navigate hundreds of meters or kilometers. In neuroscience, experiments are very different: laboratory animals are tracked inside small ~1×1-meter boxes, while recording the activity of navigation-related neurons – such as place cells, grid cells, head-direction cells, and border cells. However, it is unknown whether these spatial neurons, as studied in small laboratory-sized environments over 50 years, are relevant to large-scale navigation in the real world – outdoors. In this proposal we will address this major gap, by conducting the first ever neural…

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