Danzl Lab

Institute of Science and Technology Austria

Ostösterreich (AT1) · Austria

ERC-funded
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ERC Advanced Grant · 2024

Molecularly informed dense connectomic mapping of mammalian brain tissue

Complex wiring between neurons underlies the information processing network enabling all brain function. Fundamental questions on how the network is organized, how structural connectivity relates to the cells’ molecular machineries and how cells, synaptic connections, and circuits evolve over time remain enigmatic. Addressing these questions is beyond the limits of current measurement technologies, as these either lack resolving power to untangle cellular connectivity or can’t visualize the molecular characteristics of cells, such that these functionally highly interlinked modalities of information remain disconnected in current analysis. Here, we will devise transformative optical imaging…

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