ERC Starting Grant · 2024
Developmental Crosstalks between Microglia, Blood-Brain Barrier and Maternal Microbiota
Brain functioning can be influenced by body ecosystem signals conveyed through the vasculature and regulated by the blood-brain barrier (BBB), a selective and modulable barrier that controls which substances and cells enter the brain. Structural or functional BBB deficits are found in many brain diseases, from neurodevelopment to neurodegeneration, thus understanding how the BBB develops holds critical significance for both biologists and clinicians. Yet, we still lack fundamental knowledge on how interactions between different cellular populations in coordination with environmental signals contribute to BBB construction during early development. To tackle this issue, we will focus on the…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.
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