Finkelstein Lab

Tel Aviv University

- · Israel

ERC-funded
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ERC Starting Grant · 2024

Mechanisms of memory formation in cortical networks during learning of goal-directed behaviors

A central hypothesis in neuroscience is that changes in connectivity patterns between neurons support learning and memory formation. Most methods for examining connectivity between individual neurons rely on ex vivo experiments (e.g., in brain slices). However, in vivo measurements are required to study how neurons causally influence each other's activity ('causal connectivity') in the living brain, and how these causal interactions change over time. Thus, while brain networks are among the most studied biological networks, the cellular-level patterns and dynamics of causal connectivity in vivo remain unknown. Here, I propose to study how causal connectivity between individual neurons and…

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