Schroeder Lab

University of Munich (LMU)

Bayern (DE2) · Germany

ERC-funded
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ERC Starting Grant · 2024

Internal state drivers of behavioral flexibility and their underlying neural circuitry in the zona incerta

Survival requires accurate and rapid implementation of adaptive behavior. In a world where our physiological needs and surrounding environment are ever changing, one wrong move could make the difference between life and death. How does the brain successfully compute changes in internal state and external cues, while factoring in experience, to drive the most appropriate behavioral outcome from moment-to-moment? Mounting evidence suggests that the zona incerta, a little studied region, is a central switchboard for such adaptive behavior. This subthalamic nucleus has widespread connections and was recently found to regulate an astounding range of behaviors critical for survival including…

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